High Quality 98% Cosmetic Peptide CAS 158563-45-2 Nonapeptide-1 Powder
Product Introduction
Nonapeptide-1, white cosmetic powder and high purity above 98%, consisting of nine specific amino acids with modified D-type residues inside its peptide chain. Unlike most tyrosinase-inhibiting brightening peptides that work on enzyme activity directly, this raw material targets upstream melanogenesis signaling by competitively binding MC1R receptors on melanocyte membrane and blocking the combination between α-MSH and MC1R, further cutting off cAMP signal transmission to restrain tyrosinase overexpression and excessive melanin generation fundamentally.
Features
Its core advantage lies in outstanding safety performance without cytotoxicity to pigment cells. It never triggers skin peeling, redness or pigment rebound induced by hydroquinone, high-concentration AHA or irritating brightening ingredients, so it fits sensitive, fragile and post-problem skin for long-term daily skincare formulas. Extremely low recommended dosage ranging from 10 ppm to 200 ppm in finished products effectively controls formulation cost while maintaining stable whitening efficacy against melasma, sun spots and post-inflammatory hyperpigmentation.
This water-soluble powder owns moderate chemical stability under neutral to weak alkaline environment from pH 6.0 to 8.0; it matches well with tranexamic acid, azelaic acid, niacinamide and vitamin C for synergistic brightening effect, yet formulators should avoid mixing it with strong acid, potent oxidants and powerful chelating agents to prevent ingredient deactivation.
This water-soluble powder owns moderate chemical stability under neutral to weak alkaline environment from pH 6.0 to 8.0; it matches well with tranexamic acid, azelaic acid, niacinamide and vitamin C for synergistic brightening effect, yet formulators should avoid mixing it with strong acid, potent oxidants and powerful chelating agents to prevent ingredient deactivation.
Product Application
Apart from facial brightening serums, spot creams, ampoules and brightening masks for uneven skin tone correction, Nonapeptide-1 also works as premium hair conditioning additive in shampoo and conditioner, relieving hair yellowing and pigment dullness caused by long-time UV exposure.
Besides, cosmetic foundations and brightening concealers commonly add this peptide to realize uniform natural complexion without heavy whitening burden on skin.
Basic Analysis
| Product Name | Nonapeptide-1 | ||
| CAS No. | 158563-45-2 | Batch No. | 2024051001 |
| Molecular Formula | C61H87N15O9S | Date of Producing | 2024/08/19 |
| Molecular Weight | 1206.62 | Retest Date | 2026/08/18 |
| Date of Survey | 2024/08/24 | Condition of Storage | 2~8℃ |
| Reference Standard | Enterprise Standard | ||
| Test | Specification | Result |
| Appearance | White or almost white Powder | Conform |
| Solubility | Soluble in water | Conform |
| Water Content (Karl Fischer) | ≤8.0% | 5.2% |
| Acetic Acid (By HPLC) | ≤15.0% | 9.5% |
| Peptide Purity (By HPLC) | ≥97.0% | 98.9% |
| Conclusion: the product conforms with enterprise standar and qualified | ||
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