Hot Sales Cosmetics Ingredient Beauty Acetyl Octapeptide-3 CAS 868844-74-0
Product Introduction
Acetyl Octapeptide-3 powder, also named SNAP-8, is a synthetic anti-wrinkle cosmetic peptide raw material. It presents as fine white powder and owns great water solubility.
It blocks nerve signal transmission to relax facial muscle movement, effectively smooth dynamic wrinkles. With higher activity than common anti-aging peptides, it delivers obvious anti-aging effect.
Stable in property and mild to skin, it suits all skin types. Widely used in anti-wrinkle serum, eye cream, firming cream and professional skin care products to reduce fine lines and prevent skin aging.
Features
1."Botox-like" Mechanism: It mimics the N-terminal end of the protein SNAP-25. By competing with SNAP-25, it inhibits the formation of the SNARE complex, which subsequently reduces the release of acetylcholine (Ach) and calms muscle contractions.
2.Enhanced Efficacy: As an elongated analog of Acetyl Hexapeptide-3 (Argireline), studies suggest Acetyl Octapeptide-3 exhibits higher anti-wrinkle activity and is more effective at reducing the depth of expression lines compared to its predecessor.
3.Non-Toxic & Safe: Unlike Botulinum Toxin, it is non-toxic and does not cause paralysis. Cytotoxicity tests have confirmed its safety for topical cosmetic use.
4.High Anti-Wrinkle Efficacy: Up to 63% reduction in wrinkle depth after 28 days of twice-daily use; visible improvement in 7 days.
5.Superior Stability: Easy-to-store powder, excellent formulation compatibility, long shelf life.
Product Application
Anti-Wrinkle & Anti-Aging:
Primarily used to reduce wrinkles caused by facial expression muscle contraction (dynamic wrinkles), such as frown lines, crow's feet (around the eyes), and forehead lines.
Cosmetic Formulations:
It is commonly found in serums, creams, and eye masks.
Typical Dosage: Used at concentrations ranging from 0.05% to 0.1% in finished products
1.Anti-Wrinkle Serums/Essences: Target expression lines and skin firming.
2.Eye Creams: Improve crow’s feet and fine lines around eyes, mild & gentle.
3.Anti-Aging Creams/Lotions: Full-face wrinkle reduction, skin smoothing, fine line prevention.
4.Lyophilized Powders/Ampoules: High-concentration repair for professional & premium skincare.
5.Professional Products: Post-microneedling care, ampoule solutions for enhanced penetration.
Basic Analysis
| Items | Standards | Results |
| Appearance | White to off-white powder | Complies |
| Identity by ESI-MS | Theoretical MW:1075.20 | Complies |
| Purity (HPLC) | ≥98% | 99.69% |
| Peptide Content(By N) | ≥80% | 91.02% |
| Water(K.F.) | ≤7% | 4.66% |
| Acetic acid content | ≤15.0% | 1.81% |
| Lead(mg/kg) | ≤10 | <10 |
| Arsenic (mg/kg) | ≤2 | <2 |
| Mercury (mg/kg) | ≤1 | <1 |
| Cadmium(mg/kg) | ≤5 | <5 |
| Total plate count(cfu/g) | ≤1000 | Complies |
| Yeast & mould(cfu/g) | ≤100 | Complies |
| Conclusion | Conforms to standard | Complies |
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