Inquiry
Form loading...
High-purity bioactive ingredients engineered for premium skin care formulations
Phosphatidylserine (PS) is a naturally occurring phospholipid — a class of fat molecules that form the structural backbone of every cell membrane in the human body. In skin care, pure phosphatidylserine has emerged as one of the most scientifically compelling bioactive ingredients of the decade, bridging the gap between neuroscience-derived compounds and advanced cosmetic dermatology.
Unlike many trendy actives, PS is endogenous — your skin cells already rely on it. As we age, phosphatidylserine levels in skin tissue decline, contributing to reduced membrane fluidity, impaired cellular signaling, and the visible signs of aging: fine lines, loss of elasticity, and compromised barrier function. Topically applied pure phosphatidylserine replenishes this deficit at the cellular level.
Sourced primarily from soy lecithin or sunflower lecithin via enzymatic transphosphatidylation, high-purity PS (≥97%) is now commercially available in cosmetic-grade forms suitable for serums, creams, masks, and advanced delivery systems. Its amphiphilic molecular structure — featuring both hydrophilic and lipophilic regions — makes it an exceptional emulsifier, penetration enhancer , and active ingredient simultaneously.
Pure Phosphatidylserine integrates directly into the phospholipid bilayer of skin cells, restoring membrane integrity, enhancing receptor sensitivity, and activating cellular repair pathways — a mechanism no conventional moisturizer can replicate.
PS molecules are structurally identical to those in human skin cell membranes. This bioidentical nature ensures seamless integration, minimal irritation risk, and superior bioavailability compared to synthetic alternatives.
Commercial-grade pure phosphatidylserine is derived from non-GMO soy or sunflower lecithin through enzymatic processes, aligning with the clean beauty and sustainability mandates increasingly demanded by global cosmetic brands.
Cosmetic-grade PS is typically standardized to ≥97% purity, verified by HPLC analysis. Shaanxi Qiyuan Kangjian Biotechnology supplies pharmaceutical and cosmetic grade PS with full third-party testing documentation from SGS, Eurofins, and Pony Testing.
Six clinically supported mechanisms that make PS an indispensable cosmetic active
PS reinforces the lipid bilayer of the stratum corneum, reducing transepidermal water loss (TEWL) by up to 38% in clinical studies. Ideal for sensitive, compromised, or post-procedure skin formulations.
By restoring membrane fluidity and activating protein kinase C signaling pathways, pure PS stimulates collagen synthesis and reduces the depth of established wrinkles — a dual mechanism unmatched by peptides alone.
The phospholipid structure of PS creates a reservoir effect within the stratum corneum, binding water molecules at the cellular level and delivering sustained 24-hour hydration without occlusive heaviness.
PS activates apoptotic clearance of damaged keratinocytes while simultaneously signaling stem cell differentiation — effectively accelerating skin turnover and improving texture, tone, and radiance.
As a natural liposome-forming agent, PS dramatically improves the transdermal penetration of co-formulated actives such as retinol, vitamin C, niacinamide, and growth factors — amplifying the efficacy of entire formulations.
Pure phosphatidylserine modulates cortisol-related inflammatory cascades in skin tissue, reducing redness, irritation, and stress-induced breakouts — making it particularly effective in calming and rosacea-targeted products.
Commercial and industrial landscape shaping the future of phosphatidylserine-based beauty
The global phosphatidylserine market was valued at approximately USD 780 million in 2023 and is projected to surpass USD 1.4 billion by 2030, growing at a CAGR of 8.7%. The cosmetics and personal care segment now accounts for over 22% of total PS consumption — a share that has doubled since 2018, driven by the convergence of neuroscience and skin care.
China, South Korea, and Japan collectively represent the fastest-growing regional markets for PS-based cosmetics. South Korean K-beauty brands pioneered PS incorporation into essence formulations as early as 2019, and Chinese premium skin care brands have rapidly adopted it as a hero ingredient in anti-aging serums targeting the affluent millennial demographic.
China has emerged as the dominant global supplier of cosmetic-grade pure phosphatidylserine, with Shaanxi, Shandong, and Zhejiang provinces hosting the largest production clusters. Advances in enzymatic transphosphatidylation technology have reduced production costs by 35% over five years while simultaneously raising purity standards from 70% to 97%+, making premium PS accessible to mid-market cosmetic brands.
The clean beauty movement has been a significant tailwind for PS adoption. As consumers and regulators push for ingredient transparency and natural sourcing, PS — derived from non-GMO sunflower lecithin — positions itself as a clean, vegan-friendly alternative to synthetic emulsifiers and membrane-active compounds. Leading clean beauty certifiers now recognize PS as a preferred phospholipid ingredient.
The blurring boundary between cosmetics and pharmaceuticals — the cosmeceutical space — has been particularly transformative for PS. Dermatologist-formulated products, medical-grade skin care lines, and prescription-adjacent brands are increasingly positioning pure phosphatidylserine as a clinically active ingredient, with supporting clinical trial data that meets the evidentiary standards of both cosmetic and quasi-drug regulatory frameworks.
Artificial intelligence platforms are now being deployed by major cosmetic ingredient suppliers and brands to optimize PS-based formulations. Machine learning models analyze skin microbiome data, climate variables, and demographic profiles to recommend personalized PS concentrations and delivery systems — heralding a new era of precision skin care where pure phosphatidylserine plays a central bioactive role.
From luxury serums to clinical dermatology — the expanding universe of phosphatidylserine skin care applications
Pure PS at 1–3% concentration is the cornerstone of premium anti-aging serums targeting women aged 35–60. Its ability to restore membrane fluidity synergizes with retinoids, peptides, and growth factors to deliver compounded anti-aging efficacy. Luxury brands command price premiums of 40–80% when PS is prominently featured on front-of-pack labeling, reflecting strong consumer willingness to pay for science-backed actives.
Medical aesthetics clinics and dermatology practices are adopting PS-enriched recovery creams for post-laser, post-peel, and post-microneedling protocols. PS accelerates barrier restoration by 28% compared to standard ceramide formulations, reduces downtime, and minimizes post-inflammatory hyperpigmentation — making it a preferred ingredient for aesthetic medicine professionals globally.
Daily moisturizers incorporating pure phosphatidylserine as a functional emulsifier deliver dual benefits: superior skin feel and active barrier repair. PS-stabilized emulsions exhibit enhanced stability, reduced preservative requirements, and improved sensory profiles — advantages that resonate with both formulators and eco-conscious consumers seeking minimalist, high-performance skin care.
Overnight formulations represent an ideal application vehicle for pure PS. During sleep, skin enters an accelerated repair phase with elevated cellular turnover and increased membrane permeability. PS-loaded sleep masks leverage this natural biological window to maximize cellular uptake, with clinical studies showing 2.3x greater collagen stimulation from overnight PS application versus daytime use.
The delicate periorbital zone — characterized by the thinnest skin on the face, highest mechanical stress, and most visible aging signs — responds exceptionally well to pure PS. Eye creams and serums formulated with PS at 0.5–1.5% demonstrate measurable reduction in crow's feet depth, under-eye puffiness, and dark circle intensity, supported by validated clinical imaging studies.
Emerging research highlights PS's role in mitigating UV-induced cellular damage. By stabilizing cell membranes against oxidative stress and activating DNA repair signaling, PS-enriched after-sun formulations reduce erythema duration by up to 41% and significantly lower the risk of UV-triggered premature photoaging — opening a high-growth niche in the global sun care market valued at over USD 12 billion.
Pure phosphatidylserine is the preferred shell material for cosmetic liposomes and nanostructured lipid carriers (NLCs) due to its bioidentical composition and superior encapsulation efficiency. PS-based liposomes achieve 3–5x greater dermal penetration depth compared to conventional lecithin liposomes, enabling the effective delivery of otherwise poorly bioavailable actives such as coenzyme Q10, astaxanthin, and resveratrol.
High-end spa brands and professional aesthetic treatment lines are incorporating pure PS into facial treatment ampoules, sheet masks, and microcurrent-activating serums. The ingredient's ability to enhance cellular electrical conductivity makes it particularly synergistic with electroporation, iontophoresis, and microcurrent facial devices — a fast-growing segment of the professional beauty equipment market.
Located in Xi'an, Shaanxi Province, China, Shaanxi Qiyuan Kangjian Biotechnology Co., Ltd. specializes in supplying peptides, food additives, nutritional supplements, traditional Chinese medicine (TCM) extracts, plant extracts, and natural active ingredients — including cosmetic-grade pure phosphatidylserine for skin care applications.
Guided by the corporate philosophy of "rooted in our initial vision, empowered by biotechnology; upholding integrity and taking steady action to benefit the people" and the belief that "quality is our lifeline," the company leverages its group operating model and global distribution network to serve clients across the pharmaceutical, health product, and cosmetics industries.
Our team members are thoroughly familiar with the trade policies and compliance requirements of various countries. We always prioritize customer needs, strictly control quality, and respond efficiently. From order negotiation to after-sales follow-up, dedicated personnel handle the entire process — using professionalism and integrity to build bridges for cross-border cooperation and help partners explore global business opportunities.
Our R&D specialists bring deep expertise in phospholipid chemistry, cosmetic formulation science, and regulatory affairs across EU, US, and Asian markets — ensuring that every batch of pure phosphatidylserine we supply meets the precise specifications demanded by world-class skin care brands.
Contact Us →The company operates two major production bases in Weinan and Xianyang. Weinan Shenhekang Bioengineering Co., Ltd., established in 2022, boasts a 6,000-square-meter GMP-compliant production workshop equipped with state-of-the-art bioextraction and purification technology.
This base is equipped with multi-functional plant extraction equipment for extraction, separation, concentration, and drying, as well as a complete production line, with an annual processing capacity of nearly 3,000 tons of various traditional Chinese medicinal materials and the production of 300 tons of raw materials — including high-purity phosphatidylserine for cosmetic and pharmaceutical applications.
The company maintains an independent R&D team and a standardized laboratory equipped with advanced testing instruments, including thin-layer chromatography (TLC), high-performance liquid chromatography (HPLC), ultraviolet-visible spectrophotometer (UV), and gas chromatography (GC), implementing strict technical control over the entire production process from raw material collection to finished product delivery.
The company has established in-depth strategic partnerships with internationally renowned third-party testing organizations such as SGS, Eurofins, Layan Testing, and Pony Testing to ensure rigorous product quality management — providing cosmetic brands with the documentation confidence required for global market entry.
Trusted by cosmetic, pharmaceutical, and health product brands across 36+ countries
Adhering to the corporate philosophy of "rooted in our initial vision, empowered by biotechnology; upholding integrity and taking steady action to benefit the people" and the belief that "quality is our lifeline," the company leverages its group operating model and global distribution network to serve clients in the pharmaceutical, health product, and cosmetics industries — delivering pure phosphatidylserine and other bioactive ingredients that meet the most demanding formulation standards worldwide.
Its products have gained global recognition and are exported to over 36 countries in Asia, the Middle East, Europe, North America, Latin America, and Africa. With independent import and export licenses, the company has established strong partnerships with international express companies and air and sea freight forwarders to provide timely and professional services. The company also offers a comprehensive sales and service system, including OEM customization services and tailored solutions for clients with new product ideas but lacking laboratory equipment and human resources.
Explore our complete range of high-purity PS ingredients for every skin care application
