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Wholesale Cosmetic Grade L-Ergothioneine 99% CAS 497-30-3 from China Suppliers and Factory for Whitening
🔬 Product Introduction
Ergothioneine Powder is a naturally occurring amino acid-derived antioxidant primarily sourced from mushrooms (such as shiitake), fermented grains, and certain microorganisms. Unlike synthetic antioxidants, it is a unique “intracellular antioxidant” that can penetrate skin cells and mitochondria, where it neutralizes free radicals at the source.
Produced via advanced bio-fermentation technology, our ergothioneine powder retains high bioactivity and stability. It is a white, odorless fine powder with excellent solubility in water-based skincare formulations, making it a star ingredient for high-end anti-aging and protective skincare products.
✨ Features
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1. Superior Antioxidant Capacity
It neutralizes multiple free radicals (including hydroxyl radicals and superoxide anions) more effectively than vitamin C and E, and it does not oxidize itself after reaction—providing long-lasting protection instead of one-time scavenging.
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2. Mitochondrial Protection & Anti-Aging
It specifically accumulates in cell mitochondria (the "energy factory"), reduces oxidative damage to mitochondrial DNA, slows down cellular senescence, and maintains skin firmness and vitality.
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3. Stable & Light-Resistant
Unlike vitamin C, it is not easily degraded by light, heat, or air. It remains active in skincare formulations for a long time, suitable for transparent packaging products.
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4. Gentle & Skin-Friendly
Non-irritating, non-sensitizing, and compatible with all skin types—including sensitive, rosacea-prone, and post-procedure skin. It complements other active ingredients without causing conflicts.
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5. Synergistic Enhancement
When combined with other antioxidants (e.g., ferulic acid, glutathione) or peptides, it doubles the anti-aging and protective effects of the entire formulation.
🧴 Product Application
1. Skincare Formulations (Core Application):
a. Daily protective products:
Toners, moisturizers, sunscreens (boosts UV damage resistance, prevents photoaging).
b. Anti-aging treatments:
Serums, ampoules, overnight masks (targets fine lines, dullness, and skin sagging caused by oxidative stress).
c. Sensitive skin care:
Calming lotions, post-sun repair products (soothes inflammation, strengthens fragile barriers without irritation).
d. Professional salon products:
Custom facial masks, anti-aging peels (enhances the efficacy of other active ingredients like vitamin C and peptides).
📊 Basic Analysis
| General Information | |||
| Product Name: | L-(+)-Ergothioneine | Processing: | Fermentation |
| Molecular Formula: | C9H15N302S | CAS No: | 497-30-3 |
| Batch Number: | PC-AL2606009 | MFG Date: | 2024.05.30 |
| Item | Specification | Result | Method |
| Physical and Chemical Property | |||
| Appearance | White Powder | Conforms | Visual |
| Structure Identification | It matches the MRI popper | Conforms | NMR |
| Identification | Shall meet the control article | Conforms | R |
| Loss on Drying | ≤1.0g/100g | 0.10g/100g | 3g/105℃/2hrs |
| Purity | ≥ 99% | 99.90% | HPLC |
| Specifc Rotation | ≥(+)122° | 128° | Photometric Method CP202 |
| Heavy Metals | |||
| Alcohol solvent residue | ≤200mg/kg | Conforms | GC |
| Lead(Pb) | ≤1.00ppm | Conforms | ICP-MS |
| Arsenic (As) | ≤1.00ppm | Conforms | ICP-MS |
| Cadmium (Cd) | ≤0.50ppm | Conforms | ICP-MS |
| Mercury (Hg) | ≤0.10ppm | Conforms | ICP-MS |
| Microbiological Tests | |||
| Total Plate Count | ≤500cfu/g | 50cfu/g | AOAC 990.12 |
| Total Yeast& Mold | ≤10cfu/g | Conforms | AOAC 997.02 |
| E.Coli. | Negative | Conforms | AOAC 991.14 |
| Salmonella | Negative | Conforms | AOAC 998.09 |
| Staphylococcus | Negative | Conforms | AOAC 2003.07 |
| Product Status | |||
| Condusion: | Sample Qualified | ||
| ShelfLife: | 24months under the coditions below and in original packaging | ||
| Retest date: | Retest every 24 months under the conditions below and in its original packaging | ||
| Storage: | Store in a cool, dry place | ||
🏆 Why Choose Us
❓ Frequently Asked Questions
What is Ergothioneine Powder and where is it sourced from?
Ergothioneine Powder is a naturally occurring amino acid-derived antioxidant primarily sourced from mushrooms (like shiitake), fermented grains, and certain microorganisms.
How does Ergothioneine differ from Vitamin C in skincare?
Unlike Vitamin C, it neutralizes free radicals without oxidizing itself, providing long-lasting protection. It is also highly stable and not easily degraded by light, heat, or air.
Is Ergothioneine safe for sensitive skin?
Yes, it is extremely gentle, non-irritating, and non-sensitizing. It is fully compatible with all skin types, including sensitive, rosacea-prone, and post-procedure skin.
What are the main skincare applications for this powder?
It is widely used in daily protective products like sunscreens and moisturizers, anti-aging serums, sensitive skin calming lotions, and professional salon treatments.
Can Ergothioneine be combined with other skincare ingredients?
Absolutely. When combined with other antioxidants like ferulic acid, glutathione, or peptides, it synergistically enhances the anti-aging and protective effects of the entire formulation.
What is the recommended storage condition and shelf life?
It should be stored in a cool, dry place. The shelf life is 24 months under these conditions when kept in its original packaging.



