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Wholesale Cosmetic Grade L-Ergothioneine 99% CAS 497-30-3 from China Suppliers and Factory for Whitening
Product Introduction
Ergothioneine Powder is a naturally occurring amino acid-derived antioxidant primarily sourced from mushrooms (such as shiitake), fermented grains, and certain microorganisms. Unlike synthetic antioxidants, it is a unique “intracellular antioxidant” that can penetrate skin cells and mitochondria, where it neutralizes free radicals at the source.
Produced via advanced bio-fermentation technology, our ergothioneine powder retains high bioactivity and stability. It is a white, odorless fine powder with excellent solubility in water-based skincare formulations, making it a star ingredient for high-end anti-aging and protective skincare products.
Features
1. Superior Antioxidant Capacity
It neutralizes multiple free radicals (including hydroxyl radicals and superoxide anions) more effectively than vitamin C and E, and it does not oxidize itself after reaction—providing long-lasting protection instead of one-time scavenging.
2. Mitochondrial Protection & Anti-Aging
It specifically accumulates in cell mitochondria (the "energy factory"), reduces oxidative damage to mitochondrial DNA, slows down cellular senescence, and maintains skin firmness and vitality.
3. Stable & Light-Resistant
Unlike vitamin C, it is not easily degraded by light, heat, or air. It remains active in skincare formulations for a long time, suitable for transparent packaging products.
4. Gentle & Skin-Friendly
Non-irritating, non-sensitizing, and compatible with all skin types—including sensitive, rosacea-prone, and post-procedure skin. It complements other active ingredients without causing conflicts.
5. Synergistic Enhancement
When combined with other antioxidants (e.g., ferulic acid, glutathione) or peptides, it doubles the anti-aging and protective effects of the entire formulation.
Product Application
Skincare Formulations (Core Application):
a. Daily protective products:
Toners, moisturizers, sunscreens (boosts UV damage resistance, prevents photoaging).
b. Anti-aging treatments:
Serums, ampoules, overnight masks (targets fine lines, dullness, and skin sagging caused by oxidative stress).
c. Sensitive skin care:
Calming lotions, post-sun repair products (soothes inflammation, strengthens fragile barriers without irritation).
d. Professional salon products:
Custom facial masks, anti-aging peels (enhances the efficacy of other active ingredients like vitamin C and peptides).
Basic Analysis
| General Information | |||
| Product Name: | L-(+)-Ergothioneine | Processing: | Fermentation |
| Molecular Formula: | C9H15N3O2S | CAS No: | 497-30-3 |
| Batch Number: | PC-AL2606009 | MFG Date: | 2024.05.30 |
| Item | Specification | Result | Method |
| Physical and Chemical Property | |||
| Appearance | White Powder | Conforms | Visual |
| Structure Identification | It matches the MRI popper | Conforms | NMR |
| Identification | Shall meet the control article | Conforms | IR |
| Loss on Drying | ≤1.0g/100g | 0.10g/100g | 3g/105℃/2hrs |
| Purity | ≥ 99% | 99.90% | HPLC |
| Specific Rotation | ≥(+)122° | 128° | Photometric Method CP202 |
| Heavy Metals | |||
| Alcohol solvent residue | ≤200mg/kg | Conforms | GC |
| Lead (Pb) | ≤1.00ppm | Conforms | ICP-MS |
| Arsenic (As) | ≤1.00ppm | Conforms | ICP-MS |
| Cadmium (Cd) | ≤0.50ppm | Conforms | ICP-MS |
| Mercury (Hg) | ≤0.10ppm | Conforms | ICP-MS |
| Microbiological Tests | |||
| Total Plate Count | ≤500cfu/g | 50cfu/g | AOAC 990.12 |
| Total Yeast & Mold | ≤10cfu/g | Conforms | AOAC 997.02 |
| E.Coli. | Negative | Conforms | AOAC 991.14 |
| Salmonella | Negative | Conforms | AOAC 998.09 |
| Staphylococcus | Negative | Conforms | AOAC 2003.07 |
| Product Status | |||
| Conclusion: | Sample Qualified | ||
| Shelf Life: | 24 months under the conditions below and in original packaging | ||
| Retest date: | Retest every 24 months under the conditions below and in its original packaging | ||
| Storage: | Store in a cool, dry place | ||
Why Choose Us
Frequently Asked Questions
What is Ergothioneine Powder and where does it come from?
Ergothioneine Powder is a naturally occurring amino acid-derived antioxidant. It is primarily sourced from mushrooms (such as shiitake), fermented grains, and certain microorganisms using advanced bio-fermentation technology.
How is Ergothioneine different from Vitamin C?
Unlike Vitamin C, Ergothioneine is highly stable and not easily degraded by light, heat, or air. It neutralizes free radicals more effectively without oxidizing itself after the reaction, providing long-lasting, continuous protection rather than one-time scavenging.
Is it safe for sensitive or rosacea-prone skin?
Yes, it is extremely gentle and skin-friendly. It is non-irritating, non-sensitizing, and fully compatible with all skin types, including sensitive skin, rosacea-prone skin, and skin recovering from cosmetic procedures.
How does it function as an anti-aging ingredient?
As a unique "intracellular antioxidant," it penetrates skin cells and accumulates specifically in mitochondria (the cell's energy factory). Here, it reduces oxidative damage to mitochondrial DNA, slows down cellular senescence, and maintains skin firmness.
Can it be combined with other active skincare ingredients?
Absolutely. It has excellent synergistic properties. When combined with other antioxidants like ferulic acid, glutathione, or peptides, it can significantly boost and double the anti-aging and protective effects of the entire formulation.
What types of cosmetic products is it best suited for?
Thanks to its high stability and excellent water solubility, it is ideal for a wide range of products including toners, moisturizers, sunscreens, anti-aging serums, overnight masks, calming lotions, and professional salon treatments.



