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Wholesale Cosmetic Grade L-Ergothioneine 99% CAS 497-30-3
Product Introduction
Ergothioneine Powder is a naturally occurring amino acid-derived antioxidant primarily sourced from mushrooms (such as shiitake), fermented grains, and certain microorganisms. Unlike synthetic antioxidants, it is a unique “intracellular antioxidant” that can penetrate skin cells and mitochondria, where it neutralizes free radicals at the source.
Produced via advanced bio-fermentation technology, our ergothioneine powder retains high bioactivity and stability. It is a white, odorless fine powder with excellent solubility in water-based skincare formulations, making it a star ingredient for high-end anti-aging and protective skincare products
Features
1.Superior Antioxidant Capacity:
It neutralizes multiple free radicals (including hydroxyl radicals and superoxide anions) more effectively than vitamin C and E, and it does not oxidize itself after reaction—providing long-lasting protection instead of one-time scavenging.
2.Mitochondrial Protection & Anti-Aging:
It specifically accumulates in cell mitochondria (the "energy factory"), reduces oxidative damage to mitochondrial DNA, slows down cellular senescence, and maintains skin firmness and vitality.
3.Stable & Light-Resistant:
Unlike vitamin C, it is not easily degraded by light, heat, or air. It remains active in skincare formulations for a long time, suitable for transparent packaging products.
4.Gentle & Skin-Friendly:
Non-irritating, non-sensitizing, and compatible with all skin types—including sensitive, rosacea-prone, and post-procedure skin. It complements other active ingredients without causing conflicts.
5.Synergistic Enhancement:
When combined with other antioxidants (e.g., ferulic acid, glutathione) or peptides, it doubles the anti-aging and protective effects of the entire formulation.
Product Application
1.Skincare Formulations (Core Application):
a.Daily protective products:
Toners, moisturizers, sunscreens (boosts UV damage resistance, prevents photoaging).


b.Anti-aging treatments:
Serums, ampoules, overnight masks (targets fine lines, dullness, and skin sagging caused by oxidative stress).
c.Sensitive skin care:
Calming lotions, post-sun repair products (soothes inflammation, strengthens fragile barriers without irritation).
d.Professional salon products:
Custom facial masks, anti-aging peels (enhances the efficacy of other active ingredients like vitamin C and peptides).

Basic Analysis
| General Information | |||
| Product Name: | L-(+)-Ergothioneine | Processing: | Fermentation |
| Molecular Formula: | C9H15N302S | CAS No: | 497-30-3 |
| Batch Number: | PC-AL2606009 | MFG Date: | 2024.05.30 |
| Item | Specification | Result | Method |
| Physical and Chemical Property | |||
| Appearance | White Powder | Conforms | Visual |
| Structure Identification | It matches the MRI popper | Conforms | NMR |
| Identification | Shall meet the control article | Conforms | R |
| Loss on Drying | ≤1.0g/100g | 0.10g/100g | 3g/105℃/2hrs |
| Purity | ≥ 99% | 99.90% | HPLC |
| Specifc Rotation | ≥(+)122° | 128° | Photometric Method CP202 |
| Heavy Metals | |||
| Alcohol solvent residue | ≤200mg/kg | Conforms | GC |
| Lead(Pb) | ≤1.00ppm | Conforms | ICP-MS |
| Arsenic (As) | ≤1.00ppm | Conforms | ICP-MS |
| Cadmium (Cd) | ≤0.50ppm | Conforms | ICP-MS |
| Mercury (Hg) | ≤0.10ppm | Conforms | ICP-MS |
| Microbiological Tests | |||
| Total Plate Count | ≤500cfu/g | 50cfu/g | AOAC 990.12 |
| Total Yeast& Mold | ≤10cfu/g | Conforms | AOAC 997.02 |
| E.Coli. | Negative | Conforms | AOAC 991.14 |
| Salmonella | Negative | Conforms | AOAC 998.09 |
| Staphylococcus | Negative | Conforms | AOAC 2003.07 |
| Product Status | |||
| Condusion: | Sample Qualified | ||
| ShelfLife: | 24months under the coditions below and in original packaging | ||
| Retest date: | Retest every 24 months under the conditions below and in its original packaging | ||
| Storage: | Store in a cool, dry place | ||
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