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Best Price Cosmetic Peptide Skin Whitening Decapeptide-12 Powder CAS 137665-91-9

1. Product name: Decapeptide-12
2. Appearance: White Powder
3. CAS No: 137665-91-9
4. MF: C65H90N18O17
5. Purity: 99%
6. Usage: Skin Care

    Product Introduction

    Its core whitening mechanism relies on competitive combination with the copper active site of tyrosinase, the key enzyme triggering melanin synthesis. It efficiently suppresses pigment generation without damaging healthy melanocytes, avoiding common adverse reactions like ochronosis and permanent hypopigmentation caused by hydroquinone. 

    Features   

    Chemically stable across regular cosmetic pH ranges, it mixes well with niacinamide, tranexamic acid and retinol to realize synergistic brightening effects. Mild and non-irritating, it suits sensitive skin and dark skin tones for long-term daily use, requiring sealed storage at 2–8 ℃ away from direct sunlight to retain activity. 
    1. High-efficiency tyrosinase inhibition:Competitive binding with tyrosinase to block melanin synthesis.
    2. Dual-function, brightening+anti-photoaging: Eliminate free radicals and repair UV-induced skin damage.
    3. Excellent formulation compatibility: Compatible with toner, serum, cream. Synergize well with niacinamide, tranexamic acid, azelaic acid and Vitamin C. Suitable for day & night skincare formulas.
    4. Good chemical stability: Stable against moderate acid, alkali and heating during production, hardly deactivate in finished formulas, easy for large-batch cosmetic manufacturing.

    Product Application   

    The recommended addition proportion in finished cosmetics falls between 0.01% and 0.5%. Formulators regularly incorporate this powder into brightening serums, spot-removal creams, repairing facial masks and under-eye essences to improve sun spots, melasma, post-inflammatory hyperpigmentation and sallow uneven complexion. 
    Apart from concentrated skincare items, it is also applied in skincare-infused foundations and tinted moisturizers to achieve natural all-day skin tone correction and translucent brightening effects.
    Decapeptide-12 (1)
    Decapeptide-12 (2)
    1.Brightening & depigmentation skincare: Spot serum, whitening essence, melasma cream, pigmentation lotion, targeting melasma, sun spots, age spots, post-inflammatory hyperpigmentation (PIH), uneven dull skin tone; obvious pigment fading after 8–16 weeks of continuous use.
    2.Anti-aging skincare: Anti-wrinkle essence, firming cream, anti-photoaging lotion, boosts collagen & elastin synthesis, reduces fine lines and photo damage.
    3.Facial mask: Brightening mask, post-procedure repair mask for laser/peel post-inflammatory darkening repair.
    4.After-sun care: Post-sun repair essence to prevent UV-induced melanosis.
    5.Hair care: Premium scalp essence to improve scalp hyperpigmentation and uneven hair dye discoloration.

    Basic Analysis

    Product Name Decapeptide-12
    CAS No. -- Batch No. 2024051001
    Molecular Formula C65H90N18O17 Date of Producing 2024/06/20
    Molecular Weight 1395.55 Retest Date 2026/06/19
    Date of Survey 2024/06/24 Condition of Storage 2~8℃
    Reference Standard Enterprise Standard
    Test Specification Result
    Appearance White or almost white Powder Conform
    Solubility Soluble in water Conform
    Water Content (Karl Fischer) ≤8.0% 4.30%
    Acetic Acid (By HPLC) ≤15.0% 13.20%
    Peptide Purity (By HPLC) ≥97.0% 99.40%
    Conclusion: the product conforms with enterprise standar and qualified

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