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High Purity Acetyl Octapeptide-3 99% CAS 868844-74-0 - Leading China Suppliers & Factory for Skin Care
Product Introduction
Acetyl Octapeptide-3 powder, also named SNAP-8, is a synthetic anti-wrinkle cosmetic peptide raw material. It presents as fine white powder and owns great water solubility.
It blocks nerve signal transmission to relax facial muscle movement, effectively smooth dynamic wrinkles. With higher activity than common anti-aging peptides, it delivers obvious anti-aging effect.
Stable in property and mild to skin, it suits all skin types. Widely used in anti-wrinkle serum, eye cream, firming cream and professional skin care products to reduce fine lines and prevent skin aging.
Features
"Botox-like" Mechanism: It mimics the N-terminal end of the protein SNAP-25. By competing with SNAP-25, it inhibits the formation of the SNARE complex, which subsequently reduces the release of acetylcholine (Ach) and calms muscle contractions.
Enhanced Efficacy: As an elongated analog of Acetyl Hexapeptide-3 (Argireline), studies suggest Acetyl Octapeptide-3 exhibits higher anti-wrinkle activity and is more effective at reducing the depth of expression lines compared to its predecessor.
Non-Toxic & Safe: Unlike Botulinum Toxin, it is non-toxic and does not cause paralysis. Cytotoxicity tests have confirmed its safety for topical cosmetic use.
High Anti-Wrinkle Efficacy: Up to 63% reduction in wrinkle depth after 28 days of twice-daily use; visible improvement in 7 days.
Superior Stability: Easy-to-store powder, excellent formulation compatibility, long shelf life.
Product Application
Anti-Wrinkle & Anti-Aging:
Primarily used to reduce wrinkles caused by facial expression muscle contraction (dynamic wrinkles), such as frown lines, crow's feet (around the eyes), and forehead lines.
Cosmetic Formulations:
It is commonly found in serums, creams, and eye masks.
Typical Dosage: Used at concentrations ranging from 0.05% to 0.1% in finished products.
- Anti-Wrinkle Serums/Essences: Target expression lines and skin firming.
- Eye Creams: Improve crow’s feet and fine lines around eyes, mild & gentle.
- Anti-Aging Creams/Lotions: Full-face wrinkle reduction, skin smoothing, fine line prevention.
- Lyophilized Powders/Ampoules: High-concentration repair for professional & premium skincare.
- Professional Products: Post-microneedling care, ampoule solutions for enhanced penetration.
Basic Analysis
| Items | Standards | Results |
|---|---|---|
| Appearance | White to off-white powder | Complies |
| Identity by ESI-MS | Theoretical MW:1075.20 | Complies |
| Purity (HPLC) | ≥98% | 99.69% |
| Peptide Content(By N) | ≥80% | 91.02% |
| Water(K.F.) | ≤7% | 4.66% |
| Acetic acid content | ≤15.0% | 1.81% |
| Lead(mg/kg) | ≤10 | <10 |
| Arsenic (mg/kg) | ≤2 | <2 |
| Mercury (mg/kg) | ≤1 | <1 |
| Cadmium(mg/kg) | ≤5 | <5 |
| Total plate count(cfu/g) | ≤1000 | Complies |
| Yeast & mould(cfu/g) | ≤100 | Complies |
| Conclusion | Conforms to standard | Complies |
Why Choose Us
Frequently Asked Questions
What is Acetyl Octapeptide-3 (SNAP-8)?
Acetyl Octapeptide-3, also known as SNAP-8, is a synthetic anti-wrinkle cosmetic peptide raw material. It is a white powder with excellent water solubility, designed to target dynamic wrinkles by mimicking the N-terminal end of SNAP-25.
How does SNAP-8 differ from Botulinum Toxin?
Unlike Botulinum Toxin, SNAP-8 is non-toxic and does not cause muscle paralysis. It works topically by competing with SNAP-25 to inhibit the formation of the SNARE complex, which naturally calms muscle contractions and reduces expression lines safely.
What is the recommended dosage of Acetyl Octapeptide-3 in formulations?
In finished cosmetic products such as serums, creams, and eye masks, the typical recommended formulation concentration ranges from 0.05% to 0.1%.
How fast can I expect to see anti-wrinkle results?
Studies show visible improvements in skin smoothness and fine lines in as little as 7 days, with up to a 63% reduction in wrinkle depth observed after 28 days of twice-daily application.
Is Acetyl Octapeptide-3 powder stable and easy to formulate?
Yes, it features superior stability, excellent compatibility with common cosmetic ingredients, and a long shelf life, making it highly suitable and easy to store for various formulation processes.