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Wholesale Cosmetic Grade L-Ergothioneine 99% CAS 497-30-3 - China Suppliers & Factory for Skin Whitening
Product Introduction
Ergothioneine Powder is a naturally occurring amino acid-derived antioxidant primarily sourced from mushrooms (such as shiitake), fermented grains, and certain microorganisms. Unlike synthetic antioxidants, it is a unique “intracellular antioxidant” that can penetrate skin cells and mitochondria, where it neutralizes free radicals at the source.
Produced via advanced bio-fermentation technology, our ergothioneine powder retains high bioactivity and stability. It is a white, odorless fine powder with excellent solubility in water-based skincare formulations, making it a star ingredient for high-end anti-aging and protective skincare products.
Features
1. Superior Antioxidant Capacity
It neutralizes multiple free radicals (including hydroxyl radicals and superoxide anions) more effectively than vitamin C and E, and it does not oxidize itself after reaction—providing long-lasting protection instead of one-time scavenging.
2. Mitochondrial Protection & Anti-Aging
It specifically accumulates in cell mitochondria (the "energy factory"), reduces oxidative damage to mitochondrial DNA, slows down cellular senescence, and maintains skin firmness and vitality.
3. Stable & Light-Resistant
Unlike vitamin C, it is not easily degraded by light, heat, or air. It remains active in skincare formulations for a long time, suitable for transparent packaging products.
4. Gentle & Skin-Friendly
Non-irritating, non-sensitizing, and compatible with all skin types—including sensitive, rosacea-prone, and post-procedure skin. It complements other active ingredients without causing conflicts.
5. Synergistic Enhancement
When combined with other antioxidants (e.g., ferulic acid, glutathione) or peptides, it doubles the anti-aging and protective effects of the entire formulation.
Product Application
1. Skincare Formulations (Core Application):
a. Daily protective products:
Toners, moisturizers, sunscreens (boosts UV damage resistance, prevents photoaging).
b. Anti-aging treatments:
Serums, ampoules, overnight masks (targets fine lines, dullness, and skin sagging caused by oxidative stress).
c. Sensitive skin care:
Calming lotions, post-sun repair products (soothes inflammation, strengthens fragile barriers without irritation).
d. Professional salon products:
Custom facial masks, anti-aging peels (enhances the efficacy of other active ingredients like vitamin C and peptides).
Basic Analysis
| General Information | |||
| Product Name: | L-(+)-Ergothioneine | Processing: | Fermentation |
| Molecular Formula: | C9H15N302S | CAS No: | 497-30-3 |
| Batch Number: | PC-AL2606009 | MFG Date: | 2024.05.30 |
| Item | Specification | Result | Method |
| Physical and Chemical Property | |||
| Appearance | White Powder | Conforms | Visual |
| Structure Identification | It matches the MRI popper | Conforms | NMR |
| Identification | Shall meet the control article | Conforms | R |
| Loss on Drying | ≤1.0g/100g | 0.10g/100g | 3g/105℃/2hrs |
| Purity | ≥ 99% | 99.90% | HPLC |
| Specific Rotation | ≥(+)122° | 128° | Photometric Method CP202 |
| Heavy Metals | |||
| Alcohol solvent residue | ≤200mg/kg | Conforms | GC |
| Lead(Pb) | ≤1.00ppm | Conforms | ICP-MS |
| Arsenic (As) | ≤1.00ppm | Conforms | ICP-MS |
| Cadmium (Cd) | ≤0.50ppm | Conforms | ICP-MS |
| Mercury (Hg) | ≤0.10ppm | Conforms | ICP-MS |
| Microbiological Tests | |||
| Total Plate Count | ≤500cfu/g | 50cfu/g | AOAC 990.12 |
| Total Yeast & Mold | ≤10cfu/g | Conforms | AOAC 997.02 |
| E.Coli. | Negative | Conforms | AOAC 991.14 |
| Salmonella | Negative | Conforms | AOAC 998.09 |
| Staphylococcus | Negative | Conforms | AOAC 2003.07 |
| Product Status | |||
| Conclusion: | Sample Qualified | ||
| Shelf Life: | 24 months under the conditions below and in original packaging | ||
| Retest date: | Retest every 24 months under the conditions below and in its original packaging | ||
| Storage: | Store in a cool, dry place | ||
Why Choose Us
Frequently Asked Questions (FAQ)
What is Ergothioneine Powder and where does it come from?
Ergothioneine Powder is a naturally occurring amino acid-derived antioxidant. It is primarily sourced from mushrooms (such as shiitake), fermented grains, and certain microorganisms.
How is your Ergothioneine Powder manufactured?
Our ergothioneine powder is produced via advanced bio-fermentation technology, ensuring it retains high bioactivity, stability, and excellent solubility in water-based formulations.
How does it compare to Vitamin C for skincare?
It neutralizes multiple free radicals more effectively than Vitamin C and E. Unlike Vitamin C, it does not oxidize itself after reacting and is highly stable against light, heat, and air.
Is Ergothioneine suitable for sensitive skin?
Yes, it is non-irritating, non-sensitizing, and gentle enough for all skin types, including sensitive skin, rosacea-prone skin, and post-procedure skin repair.
Can it be mixed with other active skincare ingredients?
Absolutely. It has excellent synergistic enhancement properties. When combined with other antioxidants (like ferulic acid or glutathione) or peptides, it doubles the anti-aging and protective effects.
What is the shelf life of this product?
The product has a shelf life of 24 months when stored in a cool, dry place in its original packaging. We recommend retesting every 24 months under these conditions.



