Wholesale L-Ergothioneine 99% Suppliers in China - Cosmetic Grade White Powder from Factory CAS 497-30-3
Product Introduction
Ergothioneine Powder is a naturally occurring amino acid-derived antioxidant primarily sourced from mushrooms (such as shiitake), fermented grains, and certain microorganisms. Unlike synthetic antioxidants, it is a unique “intracellular antioxidant” that can penetrate skin cells and mitochondria, where it neutralizes free radicals at the source.
Produced via advanced bio-fermentation technology, our ergothioneine powder retains high bioactivity and stability. It is a white, odorless fine powder with excellent solubility in water-based skincare formulations, making it a star ingredient for high-end anti-aging and protective skincare products.
Features
It neutralizes multiple free radicals (including hydroxyl radicals and superoxide anions) more effectively than vitamin C and E, and it does not oxidize itself after reaction—providing long-lasting protection instead of one-time scavenging.
It specifically accumulates in cell mitochondria (the "energy factory"), reduces oxidative damage to mitochondrial DNA, slows down cellular senescence, and maintains skin firmness and vitality.
Unlike vitamin C, it is not easily degraded by light, heat, or air. It remains active in skincare formulations for a long time, suitable for transparent packaging products.
Non-irritating, non-sensitizing, and compatible with all skin types—including sensitive, rosacea-prone, and post-procedure skin. It complements other active ingredients without causing conflicts.
When combined with other antioxidants (e.g., ferulic acid, glutathione) or peptides, it doubles the anti-aging and protective effects of the entire formulation.
Product Application
Basic Analysis
| General Information | |||
| Product Name: | L-(+)-Ergothioneine | Processing: | Fermentation |
| Molecular Formula: | C9H15N302S | CAS No: | 497-30-3 |
| Batch Number: | PC-AL2606009 | MFG Date: | 2024.05.30 |
| Item | Specification | Result | Method |
| Physical and Chemical Property | |||
| Appearance | White Powder | Conforms | Visual |
| Structure Identification | It matches the MRI popper | Conforms | NMR |
| Identification | Shall meet the control article | Conforms | R |
| Loss on Drying | ≤1.0g/100g | 0.10g/100g | 3g/105℃/2hrs |
| Purity | ≥ 99% | 99.90% | HPLC |
| Specifc Rotation | ≥(+)122° | 128° | Photometric Method CP202 |
| Heavy Metals | |||
| Alcohol solvent residue | ≤200mg/kg | Conforms | GC |
| Lead(Pb) | ≤1.00ppm | Conforms | ICP-MS |
| Arsenic (As) | ≤1.00ppm | Conforms | ICP-MS |
| Cadmium (Cd) | ≤0.50ppm | Conforms | ICP-MS |
| Mercury (Hg) | ≤0.10ppm | Conforms | ICP-MS |
| Microbiological Tests | |||
| Total Plate Count | ≤500cfu/g | 50cfu/g | AOAC 990.12 |
| Total Yeast& Mold | ≤10cfu/g | Conforms | AOAC 997.02 |
| E.Coli. | Negative | Conforms | AOAC 991.14 |
| Salmonella | Negative | Conforms | AOAC 998.09 |
| Staphylococcus | Negative | Conforms | AOAC 2003.07 |
| Product Status | |||
| Conclusion: | Sample Qualified | ||
| Shelf Life: | 24 months under the conditions below and in original packaging | ||
| Retest date: | Retest every 24 months under the conditions below and in its original packaging | ||
| Storage: | Store in a cool, dry place | ||
Why Choose Us
Frequently Asked Questions
Ergothioneine Powder is a natural amino acid-derived intracellular antioxidant. Our product is manufactured using advanced bio-fermentation technology, ensuring high purity, stability, and biological activity suitable for premium cosmetic formulations.
Unlike Vitamin C, which degrades quickly when exposed to light and heat, Ergothioneine is highly stable and does not easily oxidize. Furthermore, it targets cellular mitochondria directly, providing longer-lasting antioxidant protection without causing irritation.
Yes, our Ergothioneine Powder is gentle, non-irritating, and non-sensitizing. It is highly compatible with all skin types, including sensitive, rosacea-prone, and post-procedure skin.
It should be stored in its original sealed packaging in a cool, dry place away from direct sunlight. Under these conditions, the product maintains a stable shelf life of 24 months.
Absolutely. Ergothioneine works synergistically with other antioxidants (such as ferulic acid and glutathione) and peptides, boosting the overall anti-aging and protective efficacy of the skincare formulation.



